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The human diabetes proteome project (HDPP): the 2014 update
ANA PAULINA BARBA DE LA ROSA
Acceso Abierto
Atribución-NoComercial-SinDerivadas
https://doi.org/10.1016/j.trprot.2015.03.001
HPP
B/D-HPP
HDPP
Diabetes
Human proteome
Islet
Blood
Network biology
"Diabetes is an increasing worldwide problem leading to major associated health issues and increased health care costs. In 2012, 9.3% of the American population was affected by diabetes, according to the American Diabetes Association, with 1.7 million of new cases since during the year (www.diabetes.org). Proteome initiatives can provide a deeper understanding of the biology of this disease and help develop more effective treatments. The collaborative effort of the Human Diabetes Proteome Project (HDPP) brings together a wide variety of complementary resources to increase the existing knowledge about both type 1 and type 2 diabetes and their related complications. The goals are to identify proteins and protein isoforms associated with the pathology and to characterize underlying disease-related pathways and mechanisms. Moreover, a considerable effort is being made on data integration and network biology. Sharing these data with the scientific community will be an important part of the consortium. Here we report on: the content of the HDPP session held at the 12th HUPO meeting in Yokohama; recent achievements of the consortium; discussions of several HDPP workshops; as well as future HDPP directions as discussed at the 13th HUPO congress in Madrid, with a special attention given to the lists of prioritized, diabetes-related proteins and the proteomic means to study them."
Elsevier Science BV
2015-12
Artículo
The Human Diabetes Proteome Project (HDPP): The 2014 update, Translational Proteomics, Volumes 8–9, 2015, Pages 1-7,
BIOLOGÍA Y QUÍMICA
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Publicaciones Científicas Biología Molecular

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