Por favor, use este identificador para citar o enlazar este ítem: http://ipicyt.repositorioinstitucional.mx/jspui/handle/1010/1330
Effects of nitrogen-doped multiwall carbon nanotubes on murine fibroblasts
José Gil Munguía López
Emilio Muñoz Sandoval
JOSUE ORTIZ MEDINA
Fernando Jaime Rodríguez Macías
Antonio de León Rodríguez
Acceso Abierto
Atribución-NoComercial-SinDerivadas
http://dx.doi.org/10.1155/2015/801606
"The effect of nitrogen-doped multiwall carbon nanotubes (CNx) on the proliferation of NIH-3T3murine fibroblasts is presented. CNTs were dispersed in distillated water and incubated with mammalian cells in order to evaluate their toxicity. Also, the influence of factors such as dosage (7 and 70 mu g/mL), exposure time (24 to 96 h), and the exposure route (before and after cell liftoff) on the cell proliferation was evaluated. When the CNx were simultaneously incubated with the cells, the control culture reached a maximum cell concentration of 1.3 x 10(5) +/- 3.4 x 10(4) cells per well at 96 h, whereas cultures with 7 mu g/mL reached a concentration of 2.6 x 10(4) +/- 5.3 x 10(3) cells. In the case of 70 mu g/mL of CNx most of the cells were dead. The CNx that were added 24 h after cell dissociation showed that live cells decreased, with a cell concentration of 9.6 x 10(4) +/- 9 x 10(3) for 7 mu g/mL and 5.5 x 10(4) +/- 9.5 x 10(3) for 70 mu g/mL, in contrast to control cultures with 1.1 x 10(6) +/- 1.5 x 10(4). The results showed that the CNx had cytotoxic effects depending on the concentration and exposure route."
Hindawi Publishing Corporation
2015
Artículo
Inglés
Público en general
J. G. Munguía-Lopez, E. Muñoz-Sandoval, J. Ortiz-Medina, F. J. Rodriguez-Macias, and A. De Leon-Rodriguez, “Effects of Nitrogen-Doped Multiwall Carbon Nanotubes on Murine Fibroblasts,” Journal of Nanomaterials, vol. 2015, Article ID 801606, 7 pages, 2015. doi:10.1155/2015/801606
CIENCIAS TECNOLÓGICAS
Versión publicada
publishedVersion - Versión publicada
Aparece en las colecciones: Publicaciones Científicas Biología Molecular

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