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Dynamic infrared thermography of nanoheaters embedded in skin-equivalent phantoms | |
KARLA ALEJANDRA LOPEZ VARELA NICOLAS CAYETANO CASTRO ELEAZAR SAMUEL KOLOSOVAS MACHUCA Francisco Gonzalez Fernando Sebastián Chiwo JOSE LUIS RODRIGUEZ LOPEZ | |
Acceso Abierto | |
Atribución-NoComercial-SinDerivadas | |
https://doi.org/10.1155/2018/3847348 | |
Gold nanoparticles In-vivo Photothermal therapy Drug-delivery Hepes buffer Nanomaterials Nanostars Cancer Seed Nanocrystals | |
"Nanoheaters are promising tools for localized photothermal therapy (PTT) of malignant cells. The anisotropic AuNPs present tunable surface plasmon resonances (SPR) with ideal NIR optical response to be applied as theranostic agents. To this purpose, nanoparticles with branches are suitable because of the electromagnetic field concentrated at their vertices. We standardized a protocol to synthesize multibranched gold nanoparticles (MB-AuNPs) by the seed-growth method and found a size-seed dependence tunability on the hierarchy of branching. Once the optical response is evaluated, we tested the temporal stability as nanoheaters of the MB-AuNPs immersed in skin-equivalent phantoms by dynamic infrared thermography (DIRT). The most suited sample presents a concentration of 5.2 x 10(8) MB-AuNPs/mL showing good thermal stability with Delta T = 4.5 degrees C, during 3 cycles of 10 min at 785 nm laser irradiation with power of 0.15 W. According to these results, the MB-AuNPs are suitable nanoheaters to be tested for PTT in more complex models." | |
Hindawi Publishing Corporation | |
2018 | |
Artículo | |
K. A. López-Varela, N. Cayetano-Castro, E. S. Kolosovas-Machuca, F. J. González, F. S. Chiwo, and J. L. Rodríguez-López, “Dynamic Infrared Thermography of Nanoheaters Embedded in Skin-Equivalent Phantoms,” Journal of Nanomaterials, vol. 2018, Article ID 3847348, 8 pages, 2018. https://doi.org/10.1155/2018/3847348. | |
CIENCIAS TECNOLÓGICAS | |
Versión publicada | |
publishedVersion - Versión publicada | |
Aparece en las colecciones: | Publicaciones Científicas Nanociencias y Materiales |
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